产品货号：
Z20714
中文名称：
mGluR2/GRM2抗体
英文名称：
Anti-mGluR2/GRM2 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-mGluR2/GRM2 Antibody |
| 指标别名 | GLUR2;GPRC1B;GRM2;mGlu2;mGluR2 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC,FCM(Intracellular),ELISA |
| 基因名称 | GRM2 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human Metabotropic glutamate receptor 2/GRM2 recombinant protein (Position:N439-A710). |
| 实际分子量 | 100KD,>200KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Metabotropic glutamate receptor 2 (mGluR2) is a protein that,in humans,is encoded by the GRM2 gene.It is mapped to 3p21.2.L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors.Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions.The metabotropic glutamate receptors are a family of G protein-coupled receptors,that have been divided into 3 groups on the basis of sequence homology,putative signal transduction mechanisms,and pharmacologic properties.Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C.Group II includes GRM2 and GRM3 while Group III includes GRM4,GRM6,GRM7 and GRM8.Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities.Several transcript variants encoding different isoforms have been found for this gene. |
| Uniprot ID | Q14416 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 Flow Cytometry(Intracellular) 1～3μg/1×106 cells ELISA： 1:100～1000 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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